Pronunciation: meh-DROX-ee-pro-JESS-tuh-rone
Generic Name: Medroxyprogesterone
Brand Name: Provera
Medroxyprogesterone is used for:
Treating certain menstrual problems or uterine problems (eg, abnormal bleeding, endometrial hyperplasia). It may also be used for other conditions as determined by your doctor.
Medroxyprogesterone is a progestin hormone. It works by altering the lining of the uterus.
Do NOT use Medroxyprogesterone if:
- you are allergic to any ingredient in Medroxyprogesterone
- you have vaginal bleeding of unknown cause, or if you have a history of blood clots, bleeding in the brain (eg, stroke), liver problems, or breast or genital cancer.
- you are pregnant or may be pregnant.
Contact your doctor or health care provider right away if any of these apply to you.
Before using Medroxyprogesterone:
Some medical conditions may interact with Medroxyprogesterone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, seizures (eg, epilepsy), migraines, asthma, heart problems, kidney problems, or a history of depression.
Some MEDICINES MAY INTERACT with Medroxyprogesterone. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aminoglutethimide or rifampin because they may decrease Medroxyprogesterone's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Medroxyprogesterone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Medroxyprogesterone:
Use Medroxyprogesterone as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Medroxyprogesterone. Talk to your pharmacist if you have questions about this information.
- Take Medroxyprogesterone by mouth with or without food.
- Take Medroxyprogesterone at the same time every day, with doses not more than 24 hours apart.
- If you miss a dose of Medroxyprogesterone, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Medroxyprogesterone.
Important safety information:
- Medroxyprogesterone may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Medroxyprogesterone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Medroxyprogesterone may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
- Diabetes patients - Medroxyprogesterone may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Medroxyprogesterone should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use Medroxyprogesterone if you are pregnant. If you think you may be pregnant, contact your doctor right away. Medroxyprogesterone is found in breast milk. If you are or will be breast-feeding while you are using Medroxyprogesterone, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of Medroxyprogesterone:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Acne; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; dizziness; drowsiness; fever; headache; hot flashes; nausea; nervousness; pain; rash; sleeplessness; stomach pain; weakness; weight gain or loss.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; depression; lumps in the breast or under the armpits; partial or complete loss of vision or changes in vision; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache; swelling of fingers or ankles; tenderness, pain, or swelling of the calf; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Medroxyprogesterone side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org ), or emergency room immediately.
Proper storage of Medroxyprogesterone:
Store Medroxyprogesterone in a tightly closed container at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Medroxyprogesterone out of the reach of children and away from pets.
General information:
- If you have any questions about Medroxyprogesterone, please talk with your doctor, pharmacist, or other health care provider.
- Medroxyprogesterone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Medroxyprogesterone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Medroxyprogesterone resources
- Medroxyprogesterone Side Effects (in more detail)
- Medroxyprogesterone Dosage
- Medroxyprogesterone Use in Pregnancy & Breastfeeding
- Drug Images
- Medroxyprogesterone Drug Interactions
- Medroxyprogesterone Support Group
- 150 Reviews for Medroxyprogesterone - Add your own review/rating
- Medroxyprogesterone Prescribing Information (FDA)
- Depo-Provera Prescribing Information (FDA)
- Depo-Provera Consumer Overview
- Depo-SubQ Provera 104 Prescribing Information (FDA)
- Medroxyprogesterone Acetate Monograph (AHFS DI)
- Provera Advanced Consumer (Micromedex) - Includes Dosage Information
- Provera Prescribing Information (FDA)
- medroxyprogesterone Intramuscular Advanced Consumer (Micromedex) - Includes Dosage Information
Compare Medroxyprogesterone with other medications
- Abnormal Uterine Bleeding
- Amenorrhea
- Birth Control
- Endometrial Cancer
- Endometrial Hyperplasia, Prophylaxis
- Endometriosis
- Renal Cell Carcinoma
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